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Figure 1: MRI examination, axial T2-weighted (a), T1-weighted (b), diffusion-weighted (c), and T1-weighted contrast-enhanced (d) images as well as perfusion MRI (e) and MRI spectroscopy (f). The images show diffuse hyperintensities involving the white matter, including U-fibers. There is no contrast enhancement within the affected areas (d). Perfusion MRI (e) does not reveal any regions of hyperperfusion. MRI spectroscopy (f) demonstrates a decreased N-acetyl aspartate (NAA) level, while choline (Cho) and myo-inositol (MI) peaks are increased. There is also an elevated lactate peak (Lac)

Figure 1: MRI examination, axial T2-weighted (a), T1-weighted (b), diffusion-weighted (c), and T1-weighted contrast-enhanced (d) images as well as perfusion MRI (e) and MRI spectroscopy (f). The images show diffuse hyperintensities involving the white matter, including U-fibers. There is no contrast enhancement within the affected areas (d). Perfusion MRI (e) does not reveal any regions of hyperperfusion. MRI spectroscopy (f) demonstrates a decreased N-acetyl aspartate (NAA) level, while choline (Cho) and myo-inositol (MI) peaks are increased. There is also an elevated lactate peak (Lac)