Figure 3: Histopathology and immunohistochemistry of the tumor. (a) shows highly cellular neoplastic lesion with tumor cells scant cytoplasm, hyperchromasia, and brisk mitotic activity. There is evidence of necrosis in the same (black arrow). (b) Microvascular proliferation (black arrows). (c) Hemorrhage in the tumor (black arrows). (d) Brilliant cytoplasmic positivity to glial fibrillary acid protein (GFAP). (e) Nuclear p53 reactivity. (f) Brisk IDH 1 mutation.