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Figure 2: fMRI with language paradigms. Representative images of word generation (IFG) and semantic comprehension areas (STG) in the right hemisphere in one of the adult patients (case 1) with normal speech (n = 5) preoperatively and at the last follow-up (a and b). This shows reorganization of language function following perinatal stroke in a patient who underwent surgery at the age of 20 years. (c and d) The images show partial reorganization of language function in a patient (case 11) showing bilateral activations of frontal lobe during word generation tasks. These activations were more on the left. (e and f) The images show partial reorganization of language function in the same patient (case 11) showing bilateral activations of posterior temporal lobe during semantic comprehension tasks. These activations were more on the right, unlike word generation, which correlated well with better comprehension in these patients. Representative images also show left middle frontal gyrus and IFG activation with word generation tasks in controls (g and h) and those with left STG and middle temporal gyrus activations (i and j) following semantic comprehension tasks in controls. fMRI = functional magnetic resonance imaging, IFG = inferior frontal gyrus, STG = superior temporal gyrus

Figure 2: fMRI with language paradigms. Representative images of word generation (IFG) and semantic comprehension areas (STG) in the right hemisphere in one of the adult patients (case 1) with normal speech (<i>n</i> = 5) preoperatively and at the last follow-up (a and b). This shows reorganization of language function following perinatal stroke in a patient who underwent surgery at the age of 20 years. (c and d) The images show partial reorganization of language function in a patient (case 11) showing bilateral activations of frontal lobe during word generation tasks. These activations were more on the left. (e and f) The images show partial reorganization of language function in the same patient (case 11) showing bilateral activations of posterior temporal lobe during semantic comprehension tasks. These activations were more on the right, unlike word generation, which correlated well with better comprehension in these patients. Representative images also show left middle frontal gyrus and IFG activation with word generation tasks in controls (g and h) and those with left STG and middle temporal gyrus activations (i and j) following semantic comprehension tasks in controls. fMRI = functional magnetic resonance imaging, IFG = inferior frontal gyrus, STG = superior temporal gyrus