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Figure 1: Marchiafava-Bignami disease. Case 1: (a)-Sagittal T2: Callosal hyperintensity (arrows); (b) Axial fluid attenuated inversion recovery (FLAIR): Callosal (short arrows) and subcortical white matter hyperintensity (long arrows); (c and d) Axial diffusion-weighted imaging (DWI) and apparent diffusion coefficient (ADC): restriction within the lesions (arrows); (e) Post-contrast T1: peripheral enhancement. Case 2: (f) axial T2: Callosal and periventricular white matter hyperintensity (arrows); (g and h) axial DWI: restricted diffusion in centrum semiovale and corpus callosum (arrows). Case 3: (i) sagittal T2: callosal hyperintensity (arrows); (j) axial DWI shows diffusion restriction within the genu and splenium of the corpus callosum

Figure 1: Marchiafava-Bignami disease. Case 1: (a)-Sagittal T2: Callosal hyperintensity (arrows); (b) Axial fluid attenuated inversion recovery (FLAIR): Callosal (short arrows) and subcortical white matter hyperintensity (long arrows); (c and d) Axial diffusion-weighted imaging (DWI) and apparent diffusion coefficient (ADC): restriction within the lesions (arrows); (e) Post-contrast T1: peripheral enhancement. Case 2: (f) axial T2: Callosal and periventricular white matter hyperintensity (arrows); (g and h) axial DWI: restricted diffusion in centrum semiovale and corpus callosum (arrows). Case 3: (i) sagittal T2: callosal hyperintensity (arrows); (j) axial DWI shows diffusion restriction within the genu and splenium of the corpus callosum