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Figure 3: FTY720 inactivated apoptotic and inflammatory signaling pathways. FTY720 decreased the levels of proapoptotic proteins, including cleaved caspase-3 and bax, while upregulating the level of bcl-2 (a and b). In addition, the NF-κB pathway was inactivated (c). *P < 0.05 versus the sham group; #P < 0.05 versus the SAH + saline group

Figure 3: FTY720 inactivated apoptotic and inflammatory signaling pathways. FTY720 decreased the levels of proapoptotic proteins, including cleaved caspase-3 and bax, while upregulating the level of bcl-2 (a and b). In addition, the NF-κB pathway was inactivated (c). *<i>P</i> < 0.05 versus the sham group; #<i>P</i> < 0.05 versus the SAH + saline group