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Figure 5: Transmission electron microscopy: At the 4th generation of the cultured cells, the stromal cells presented as large size cells and typical lipid droplets in cytoplasm, while, no endothelial cells and pericytes was observed (a). At the 6th generation, the intracellular lipid droplets became shrinkage (b), and till 9th generation, the autophagy of the lysosome (Black arrow) was occasionally observed adjacent to stromal cells (c). At the 10th generation, plenty of lysosomal autophagy were observed without signs of apoptosis (d). Original magnification

Figure 5: Transmission electron microscopy: At the 4<sup>th</sup> generation of the cultured cells, the stromal cells presented as large size cells and typical lipid droplets in cytoplasm, while, no endothelial cells and pericytes was observed (a). At the 6th generation, the intracellular lipid droplets became shrinkage (b), and till 9th generation, the autophagy of the lysosome (Black arrow) was occasionally observed adjacent to stromal cells (c). At the 10th generation, plenty of lysosomal autophagy were observed without signs of apoptosis (d). Original magnification