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Figure 4: Low power magnification showing sheets of plasma cells (a, 40× H and E); highly vascular tumor and no amyloid deposition seen (b, 100× H and E). High power view shows sheets of cells with eccentric round or oval nuclei, with a speckled chromatin and abundant cytoplasm suggestive of mature plasma cells including binucleate forms (c, 400× H and E); CD138 immunopositivity in almost all neoplastic cells (d, CD138 immunohistochemistry)

Figure 4: Low power magnification showing sheets of plasma cells (a, 40× H and E); highly vascular tumor and no amyloid deposition seen (b, 100× H and E). High power view shows sheets of cells with eccentric round or oval nuclei, with a speckled chromatin and abundant cytoplasm suggestive of mature plasma cells including binucleate forms (c, 400× H and E); CD138 immunopositivity in almost all neoplastic cells (d, CD138 immunohistochemistry)