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   1993| April-June  | Volume 41 | Issue 2  
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Cortical blindness : a rare presentation of moya moya disease [Letter]
A Anjaneyulu, G Bhaskar
April-June 1993, 41(2):118-119
Full text not available     [PubMed]
  1,809 0 -
Polymyositis : a clinical profile
A Thussu, S Prabhakar, SK Bansal, IMS Sawhney, JS Chopra
April-June 1993, 41(2):93-97
Clinical data of 132 patients of polymyositis seen over a period of ten years was retrospectively analysed. Important features included a mean age of 32.31 years with a range of 8 years to 70 years. 40.62 percent patients were of primary idiopathic polymyositis while 53.13 percent presented with disease of more than six months duration. Pelvic girdle weakness was demonstrated in 31 cases (96.87 percent). Creatin phosphokinase (CPK) values were consistently elevated in 81.25 percent of these cases. Electromyography in majority showed mixed neurogenic and myopathic pattern. Muscle biopsy was performed in 23 patients and all revealed changes characteristic of polymyositis. Follow up was available in 18 cases.
[ABSTRACT]   Full text not available     [PubMed]
  1,803 0 -
Prognosis in putaminal haemorrhages : clinical and CT correlation.
M Dhanaraj, CU Velmurugendran
April-June 1993, 41(2):99-100
The prognosis of twenty consecutive patients with acute spontaneous putaminal haemorrhage was studied using clinical and CT scan findings. Patients with haemorrhage of less than 4.5 cms were mostly conscious and had independent activity of daily living (ADL) at the end of 3 months; between 4.6 cms and 6 cms., they were mostly drowsy and had partly independent ADL; above 6 cms., they were in stupor or in coma with a high incidence of mortality. Early surgical intervention is advised in the last group.
[ABSTRACT]   Full text not available     [PubMed]
  1,682 0 -
Intraventricular neurocytoma : a clinical and electro-microscopic study.
TV Rao, PN JayakuJan-Mar, Y Ramamohan, NK Venkataramana, BA Chandramouli, SK Shankar, S Das, KR Vani, Vasudev Rao , Das Sarala
April-June 1993, 41(2):101-104
Intraventricular neurocytomas are rare or have been earlier misdiagnosed as Oligodendroglioma, a tumour which they closely resemble at light microscopy. Three such intraventricular tumours are described, all of which were diagnosed as Oligodendroglioma on CT scan and at routine light microscopy. The judicious use of EM for a definite diagnosis of these tumours is emphasised. Cells with multiple processes, abundant RER and dense core vesicles and profiles of axon terminals with groups of synaptic vesicles, clinches the diagnosis. Even though the prognosis of neurocytomas is generally believed to be good, it may depend on whether they have only neuronal or associated Glial differentiation.
[ABSTRACT]   Full text not available     [PubMed]
  1,666 0 -
Alexia without agraphia : a case report with CT demonstration of the lesion and review of literature.
KA KuJan-Mar, JMK Murthy, Kumar K Ashok
April-June 1993, 41(2):109-111
A case of alexia without agraphia with CT demonstration of the lesion is reported. The various types of occipital alexia and their anatomic bases have been reviewed.
[ABSTRACT]   Full text not available     [PubMed]
  1,618 0 -
Tri-o-cresyl phosphate induced neuropathy : pathological study of human sural nerve biopsy
K Srinivasan, SK Shankar
April-June 1993, 41(2):105-108
An 18 year old male who consumed food cooked in contaminated cooking oil, during an epidemic at Calcutta in 1988, developed Tri-O-Cresyl Phosphate toxicity and peripheral neuropathy. Pathological study revealed focal loss of large myelinated fibres.EM study showed accumulation of agranular reticulum in relatively preserved axons and axonal and myelin vacuolation and accumulation of dark bodies and granular transformation of axoplasm in more affected axons, similar to those described in experimentalanimals.
[ABSTRACT]   Full text not available     [PubMed]
  1,546 0 -
Elevated levels of prostaglandins E2 and F2( in human neuromuscular disorders.
SK Mishra, S KuJan-Mar, NK Menon
April-June 1993, 41(2):87-91
Prostaglandins (Pgs), especially PGE2 and F2( ( have been implicated in variety of pathological processes including proteolysis of normal and dystrophic muscle. Using a modified radioimmunoassay which did not involve extraction in organic solvents and purification, thus eliminating acid artifacts, we measured PGE2 and F2( levels in patients with myotonic (MyD), Duchenne (DMD), and limb girdle (LGD) dystrophies and amyotrophic lateral sclerosis (ALS). There was a significant increase in PGE2 and PGF2 in the muscle samples of all the disorders studied as compared to normal controls. It is proposed that increased influx of calcium activated phospholipase A2 (PLA2) leading to the accumulation of arachidonic acid and hence prostaglandins. It appears that the relative increases in PGE2 and PGF2( which are implicated in protein degradation and synthesis respectively in vitro, may reflect the extent of degeneration and regeneration occurring in the diseased muscles.
[ABSTRACT]   Full text not available     [PubMed]
  1,521 0 -
Accumulation of lipid peroxidation products in human myotonic dystrophic muscle
SK Mishra, NK Menon, C Mauldin
April-June 1993, 41(2):83-85
The possibility of oxygen radical-induced injury contributing to the pathogenesis of muscle disorders was studied. Significant increases in fluorescent lipid peroxidation products was found in the muscle samples of myotonic dystrophy (MyD) patients as compared to controls as well as patients with Duchenne Muscular dystrophy (DMD), Amyotrophic Lateral Sclerosis (ALS), Polymyositis and Limb Girdle Dystrophy (LGD). The results demonstrate the possibility that in MyD the primary genetic disorder leads to the rapid generation of oxygen radicals, tissue depletion of antioxidants followed by peroxidation of membrane lipids, impaired calcium homeostasis and finally atrophy of the muscle.
[ABSTRACT]   Full text not available     [PubMed]
  1,496 0 -
Role of urokinase in the management of experimental intraventricular hemorrhage in canine model - Part 1 : canine intraventricular blood cast model
AK Chand, D Rout
April-June 1993, 41(2):65-67
A Canine model of intraventricular blood cast was developed in nine adult dogs to study the feasibility and the benefit of Urokinase administration by intraventricular route. A simple ventricular cannulation techniques was described to inject 8cc of preformed autologous clot to develop an intraventricular "blood cast model". An indwelling ventricular catheter-reservoir system was placed for direct administration of Urokinase to induce rapid clot lysis.
[ABSTRACT]   Full text not available     [PubMed]
  1,484 0 -
Metastatic intracranial tumours : experience and review of literature.
WH Chhang, VK Kak, VK Khosla, SN Mathuriya, BS Sharma, A Pathak, MK Tewari, BI Devi, AK Banerjee, Radotra BD , BD Gupta, S Suri, Devi B Indira
April-June 1993, 41(2):73-81
Eighty five patients with histopathologically confirmed intracranial metastatic lesions were analysed retrospectively. There were 55 males and 30 females. More than half of the patients were in fourth and fifth decades. Headache (69 percent), vomiting (50 percent) and altered sensorium (46 percent) were the common presenting features. Failing vision and epileptic seizures were present in 18 percent and 15 percent of the cases, respectively. Papilloedema was present in 68 percent of patients. Motor weakness and cranial nerve involvement was found in 42 percent and 22 percent of the patients, respectively. In 87 percent of the cases the lesions were located within the cerebral hemispheres. Only 6 percent of the patients had lesions in the cerebellum. Carcinoma of the lung was responsible for 36 percent of all intracranial metastases, followed by malignancy of the gastrointestinal tract (15 percent), genito-urinary tract (7 percent) and breast (6 percent). The primary lesion could not be located in 19 percent of the cases. 80 percent patients underwent surgery and less than half of those received postoperative irradiation and chemotherapy. The immediate postoperative mortality was 21 percent. The overall survival at five years was 6 percent.
[ABSTRACT]   Full text not available     [PubMed]
  1,460 0 -
Role of urokinase in the management of experimental intraventricular hemorrhage in canine model - Part 2 : effects of direct instillation of urokinase on dissolution of an intraventricular clot.
AK Chand, D Rout
April-June 1993, 41(2):69-72
An experimental intraventricular haemorrhage (IVH) model was developed in nine adult dogs. Urokinase, a thrombolytic agent, was injected into the ventricle of five animals through a catheter-reservoir system described in the earlier part. Four canine models served as a control. The dosage determination and the methodology of instillation of urokinase were described. Following this the animals were observed for any bleeding disorder and the neurologic status. Dissolution of the clot was demonstratedin the urokinase treated dogs by serial clinical examination, Ventriculography and post mortem studies. Absence of side effects with this mode of administration was emphasised.
[ABSTRACT]   Full text not available     [PubMed]
  1,451 0 -
Cranial epidural abscess in a healthy male
A Verma, AK Mahapatra
April-June 1993, 41(2):113-115
An unusual epidural abscess in a healthy adult is reported. The obvious cause of infection was undetermined. Patient was successfully treated and remained well thereafter.
[ABSTRACT]   Full text not available     [PubMed]
  1,388 0 -
Transverse myelitis : an unusual complication of herpes zoster [Letter]
A Bhargave, A Panagariya
April-June 1993, 41(2):117-118
Full text not available     [PubMed]
  1,295 0 -
Colloid cyst-xanthogranuloma of third ventricle : a case report [Letter]
S Hiran, S Jain, A Budhiraja, M Bhalla
April-June 1993, 41(2):117-117
Full text not available     [PubMed]
  1,199 0 -
Triphasic waves in EEG, in a patient of pituitary apoplexy : a rare occurrence[Letter]
S Kaul, JMK Murthy, C Sundram, MRC Naidu, C Sundaram
April-June 1993, 41(2):120-121
Full text not available     [PubMed]
  1,116 0 -
Sylvian fissure epidermoid manifesting as psychosis [Letter]
YR Yadav, JP Kapoor, TC Kriplani, TC Kripalani
April-June 1993, 41(2):119-120
Full text not available     [PubMed]
  975 0 -
Platysmal tremor in palatal myoclonus [Letter]
OP Lekhra, SK Bansal, S Prabhakar
April-June 1993, 41(2):121-122
Full text not available     [PubMed]
  935 0 -
Online since 20th March '04
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