Open access journal indexed with Index Medicus
Users online:
9282
Home
|
Reader Login
About
Editorial board
Articles
Current Issue
Ahead of print
Archive
NSI Publications
Current Practice In Neurosciences
Progress In Clinical Neurosciences
Evolution of Neurosciences
Neurosciences India (1989)
Archive
Search
Instructions
Online Submission
Subscribe
Videos
Etcetera
Contact
Navigate
here
»
Search
»
Current Issue
»
Submit Article
»
My Preferences
Follow us on:
Export selected to
Endnote
Reference Manager
Procite
Medlars Format
RefWorks Format
BibTex Format
Access statistics : Table of Contents
2008| October-December | Volume 56 | Issue 4
Online since
January 1, 2009
Archives
Previous Issue
Next Issue
Most popular articles
Most cited articles
Show all abstracts
Show selected abstracts
Export selected to
Viewed
PDF
Cited
REVIEW ARTICLES
Diabetic and non-diabetic lumbosacral radiculoplexus neuropathy
Minal J Bhanushali, Suraj Ashok Muley
October-December 2008, 56(4):420-425
DOI
:10.4103/0028-3886.44814
PMID
:19127036
Background:
Lumbosacral radiculoplexus neuropathy (LRPN) originally described in diabetic patients is a distinct clinical condition characterized by debilitating pain, weakness and atrophy most commonly affecting the proximal thigh muscles asymmetrically. The syndrome is usually monophasic and preceded by significant weight loss (at least more than 10 lbs). Though a self-limited condition, recovery is gradual with some residual weakness. Recent advances and research has provided new insights in the pathogenesis and thereby management of this syndrome. In this paper, we review the clinical and diagnostic features as well as discuss recent insights and treatment strategies along with our experience in the management of patients with diabetic and non-diabetic LRPN.
Materials and
Methods:
Literature in English published between 1953 and 2008 was searched in the MEDLINE and Pubmed database, maintained by the US National library of medicine and National institutes of health, using key words of diabetic amyotrophy, lumbosacral radiculoplexus neuropathy, diabetic proximal neuropathy, diabetic radiculopathy and diabetic lumbosacral plexopathy. In addition, literature reported in various textbooks on peripheral neuropathy was reviewed as well.
Observation:
The diagnosis relies mostly on clinical suspicion and characteristic electromyographic findings. The exact pathogenesis of the illness remains unknown, but there seems to be a component of immune-mediated inflammatory microvasculitis which causes secondary ischemia of the lumbosacral plexus. This has prompted a trial of immunosuppressive agents (like steroids) with an attempt to alter the course of the illness. A few reports have noted that immunosuppression when instituted early in the course of the illness (within three months of symptom onset) may hasten the recovery and improve symptoms.
Conclusion:
Though the exact mechanism of LRPN in diabetic and non-diabetic patients remains unknown, new evidence alludes to an underlying inflammatory vasculitic process. Early treatment with immunosuppressants may be beneficial in some cases, although the data available at this time is limited to a small cohort of patients. The decision is individualized weighing the risks and benefits in a given patient. Future research in this direction with double-blinded case-controlled studies is required to investigate this further.
[ABSTRACT]
[FULL TEXT]
[PDF]
[CITATIONS]
[PubMed]
24,224
1,078
18
ORIGINAL ARTICLES
Dysphagia in acute stroke: Correlation with stroke subtype, vascular territory and in-hospital respiratory morbidity and mortality
Uma Sundar, Vimal Pahuja, Nishant Dwivedi, Murar E Yeolekar
October-December 2008, 56(4):463-470
DOI
:10.4103/0028-3886.44828
PMID
:19127043
Aims:
The study aimed at correlation of post-stroke dysphagia with area and volume of infarct/ bleed, and with subsequent in-hospital respiratory morbidity and mortality.
Materials and Methods:
50 patients of acute stroke were serially recruited. Standard Staff swallowing assessment was performed within 24 hours of admission along with pulse oximetry. Ischemic strokes were classified as per OCPS registry. In-hospital respiratory morbidity and mortality, mode of nutrition and disability status at discharge were noted.
Results:
21/50 (42%) patients had post-stroke dysphagia during their hospital course. Among infarcts, Total Anterior Circulation Infarcts (TACI) had 100% incidence of dysphagia, followed by Partial Anterior Circulation Infarcts (PACI-36%), Posterior Circulation infarcts (POCI-33%), and Lacunar infarcts (LACI-18%). 67% of hemorrhages had post-stroke dysphagia. Staff swallowing assessment had a sensitivity and specificity of 75% and 73% respy., for predicting respiratory morbidity. The corresponding figures for Pulse oximetry were 79% and 91%.
[ABSTRACT]
[FULL TEXT]
[PDF]
[CITATIONS]
[PubMed]
13,134
531
14
REVIEW ARTICLES
Advanced cerebral monitoring in neurocritical care
Nobl Barazangi, J Claude Hemphill III
October-December 2008, 56(4):405-414
DOI
:10.4103/0028-3886.44628
PMID
:19127034
New cerebral monitoring techniques allow direct measurement of brain oxygenation and metabolism. Investigation using these new tools has provided additional insight into the understanding of the pathophysiology of acute brain injury and suggested new ways to guide management of secondary brain injury. Studies of focal brain tissue oxygen monitoring have suggested ischemic thresholds in focal regions of brain injury and demonstrated the interrelationship between brain tissue oxygen tension (P
bt
O
2
) and other cerebral physiologic and metabolic parameters. Jugular venous oxygen saturation (SjVO
2
) monitoring may evaluate global brain oxygen delivery and consumption, providing thresholds for detecting brain hypoperfusion and hyperperfusion. Furthermore, critically low values of P
bt
O
2
and SjVO
2
have also been predictive of mortality and worsened functional outcome, especially after head trauma. Cerebral microdialysis measures the concentrations of extracellular metabolites which may be relevant to cerebral metabolism or ischemia in focal areas of injury. Cerebral blood flow may be measured in the neurointensive care unit using continuous methods such as thermal diffusion and laser Doppler flowmetry. Initial studies have also attempted to correlate findings from advanced neuromonitoring with neuroimaging using dynamic perfusion computed tomography, positron emission tomography, and Xenon computed tomography. Additionally, new methods of data acquisition, storage, and analysis are being developed to address the increasing burden of patient data from neuromonitoring. Advanced informatics techniques such as hierarchical data clustering, generalized linear models, and heat map dendrograms are now being applied to multivariable patient data in order to better develop physiologic patient profiles to improve diagnosis and treatment.
[ABSTRACT]
[FULL TEXT]
[PDF]
[CITATIONS]
[PubMed]
11,245
938
12
ORIGINAL ARTICLES
Comparison of SF-36 and WHOQOL-100 in patients with stroke
Demet Unalan, Ferhan Soyuer, Ahmet Ozturk, Selcuk Mistik
October-December 2008, 56(4):426-432
DOI
:10.4103/0028-3886.44573
PMID
:19127037
Background and Aims:
Two widely used evaluation tools for the quality of life are the 36-item Short-Form Health Survey (SF-36) and World Health Organization Quality of Life Assessment (100-item
version) (WHOQOL-100), however, these tools have not been compared for patients with stroke to date. The specific objectives of this study were: 1) to study the effect of stroke on quality of life (QOL) as measured by the SF-36 and by the WHOQOL-100, and 2) to compare these two instruments.
Settings and Design:
Seventy patients who were admitted to the
neurology clinic six months after stroke were included in this study.
Materials and Methods:
As a data-collecting device, the SF-36 and WHOQOL-100 scales were used. An additional questionnaire was administered to obtain demographic data.
Statistical Analysis:
Pearson correlation analysis was performed and Blant-Altman Plots were used. Psychometric analysis was performed.
Results:
In stroke, the most flustered domains of quality of life were vitality and general health perception fields in the SF-36 and in the WHOQL-100, independence level field, overall QOL and general health perceptions. While there was a fair degree of relationship (r= 0.25-0.50) between general health perceptions, physical, social and mental fields that were similar fields of scales, a fair and moderate to good relationship was found between different fields. Limits of agreement in similar domains of the two instruments were very large. In all four demonstrated Bland-Altman plots, there was agreement of the scales in the measurements of similar fields of quality of life.
Conclusion:
This study demonstrated that both the SF-36 and WHOQOL-100 quality of life scales are useful in the practical evaluation of patients with stroke.
[ABSTRACT]
[FULL TEXT]
[PDF]
[CITATIONS]
[PubMed]
9,279
429
17
Clinical features, laboratory data, management and the risk factors that affect the mortality in patients with postoperative meningitis
Ilknur Erdem, Tayfun Hakan, Nurgul Ceran, Fatma Metin, Seniha Senbayrak Akcay, Metin Kucukercan, M Zafer Berkman, Pasa Goktas
October-December 2008, 56(4):433-437
DOI
:10.4103/0028-3886.44629
PMID
:19127038
Background:
Nosocomial meningitis is a rare complication following neurosurgical procedures and is associated with high morbidity and mortality.
Aim:
The aim of this study was to describe the clinical characteristics and the risk factors associated with mortality in patients who developed nosocomial meningitis following neurosurgical operations.
Setting and design:
Tertiary care hospital and an observational study.
Materials and Methods:
The study subjects included 2265 patients who underwent various neurosurgical operations during 2003-05. The diagnosis of nosocomial meningitis was based on the Center for Disease Control criteria.
Statistical analysis:
It was performed by using Statistical Package for Social Sciences for Windows 10.0 program.
Results:
The incidence of postoperative nosocomial meningitis was 2.7% (62 episodes in 49 patients among 2265 patients operated).
Staphylococcus aureus
and
Acinetobacter
spp. were the most frequently isolated pathogens. Of the 49 with meningitis 20 (40.8%) patients died. In the logistic regression analysis model, Glascow coma scale score less than 10 (Odds Ratio (OR): 19.419, 95% Confidence Interval (CI); 1.637-230.41,
P
= 0.001), and low cerebrospinal fluid glucose level (≤ 30 mg/ dL) (OR: 10.272, 95% CI; 1.273-82.854,
P
= 0.002), and presence of concurrent nosocomial infection (OR: 28.744, 95% CI;1.647-501.73,
P
=0.001) were the independent risk factors associated with mortality.
Conclusion:
The mortality in patients who developed meningitis was high. The high percentage of concurrent nosocomial infections was associated with a high mortality rate which was a serious problem.
[ABSTRACT]
[FULL TEXT]
[PDF]
[CITATIONS]
[PubMed]
9,230
463
36
CASE REPORTS
Hypersexuality following subthalamic nucleus stimulation for
Parkinson's disease
Paresh Doshi, Pranshu Bhargava
October-December 2008, 56(4):474-476
DOI
:10.4103/0028-3886.44830
PMID
:19127045
Subthalamic nucleus (STN) stimulation is an established surgical treatment for Parkinson's disease (PD). Though the motor benefits of STN stimulation are well understood, its cognitive and behavioral effects are still not fully understood. Manic psychosis, hypersexuality, pathological gambling and mood swings are associated with advanced PD. There have been reports to suggest improvement or worsening in these symptoms following STN deep brain stimulation (DBS). We report two cases as the sole behavioral side-effects of STN stimulation despite good clinical improvement on long-term follow-up. These patients and literature review suggests the complex role of STN stimulation in motor and behavioral control.
[ABSTRACT]
[FULL TEXT]
[PDF]
[CITATIONS]
[PubMed]
8,698
344
38
LETTERS TO EDITOR
Acute lithium toxicity: Two cases with different outcomes
S Pandey, S Jain, R Chatterjee
October-December 2008, 56(4):484-485
DOI
:10.4103/0028-3886.44816
PMID
:19127050
[FULL TEXT]
[PDF]
[CITATIONS]
[PubMed]
8,232
255
5
OBITUARIES
A Eulogy for Dr. Setti S. Rengachary, 1937-2008
Sunil Manjila
October-December 2008, 56(4):501-502
DOI
:10.4103/0028-3886.44808
PMID
:19127061
[FULL TEXT]
[PDF]
[PubMed]
8,013
183
-
ORIGINAL ARTICLES
Cryptococcal meningitis in HIV infected: Experience from a North Indian tertiary center
Susheel Kumar, Ajay Wanchu, Arunaloke Chakrabarti, Aman Sharma, Pradeep Bambery, Surjit Singh
October-December 2008, 56(4):444-449
DOI
:10.4103/0028-3886.44823
PMID
:19127040
Background:
Cryptococcal meningitis is a common opportunistic infection in Human Immunodeficiency Virus (HIV)-infected individuals. There is little information specifically addressing cryptococcal meningitis in HIV-infected patients from North India.
Aims:
To determine clinical presentation, hospital course, response to treatment, complications developed, in-hospital mortality, any recurrence of cryptococcal meningitis and reasons of recurrence during follow-up.
Settings and Design:
A retrospective observational study undertaken in a large tertiary care center.
Materials and Methods:
Patient's demographic data, presenting clinical symptomatology, physical findings, laboratory parameters, cerebrospinal fluid (CSF) examination findings, side-effects of treatment, development of any complications and hospital outcome were analyzed. During follow-up any recurrence of cryptococcal meningitis, possible reasons of recurrence, type of treatment received, complications developed and outcome was recorded as well.
Results:
Forty patients diagnosed to have cryptococcal meningitis were analyzed. Twenty-two (55%) patients had acute/ subacute presentation. Thirty-six (90%) patients presented with headache and 18 (45%) had altered sensorium. Twenty (50%) patients had no cells in the CSF. Hypoglycorrhchia was seen in 30 (75%) patients. Cryptococcal meningitis was the first acquired immune deficiency syndrome (AIDS)-defining illness in 30 (75%) patients. Thirty-five patients developed some adverse effects to amphotericin-B. Thirty-three patients improved with treatment while three patients died. Four patients had recurrence of cryptococcal meningitis within six months of first episode. Non-compliance of fluconazole therapy was the reason for recurrence in all of these patients.
Conclusions:
Cryptococcal meningitis is a common initial AIDS-defining illness. Acute and/or subacute presentation of cryptococcal meningitis is not uncommon in HIV-infected individuals. An early diagnosis of HIV infection might reduce the incidence of this infection.
[ABSTRACT]
[FULL TEXT]
[PDF]
[CITATIONS]
[PubMed]
7,539
546
18
REVIEW ARTICLES
Platelet glycoprotein IIb/IIIa inhibitors in acute ischemic stroke
Sudhir Kumar, G Rajshekher, Subhashini Prabhakar
October-December 2008, 56(4):399-404
DOI
:10.4103/0028-3886.44571
PMID
:19127033
Acute ischemic stroke (AIS) is a common cause of morbidity and mortality worldwide. Thrombolytic therapy with tissue plasminogen activator, the only approved treatment for AIS, is received by less than 2% of patients. Moreover, there is a slight increase in hemorrhagic complications with thrombolysis. Therefore, there is a need for newer therapeutic modalities in AIS, which could be used in window periods beyond 3-6 h after stroke onset with fewer hemorrhagic complications. Glycoprotein IIb/IIIa inhibitors (GPI), after their initial success in patients with acute coronary syndromes, promised much in patients with AIS over the past decade or so. However, their exact role in patients with AIS, including the window periods and type of strokes, and the risk of symptomatic or asymptomatic hemorrhage are unclear at the moment. The current review focuses on the literature concerning the use of GPI in AIS and looks at the available evidence regarding their use. Abciximab thought to be safe and effective in initial case series and early trials, has not been shown to improve outcomes in AIS, and is associated with higher rates of hemorrhage. Tirofiban appears to be safe and effective in initial trials and there is a need to conduct further trials to establish its role in AIS.
[ABSTRACT]
[FULL TEXT]
[PDF]
[CITATIONS]
[PubMed]
6,701
738
6
Prehospital care of head injured patients
Hari H Dash
October-December 2008, 56(4):415-419
DOI
:10.4103/0028-3886.44812
PMID
:19127035
Resuscitation of head injured patients at the accident site is paramount in minimizing morbidity and mortality. This can be achieved through prehospital care which is nonexistent in our country. This review is a step forward, so that we can formulate guidelines in this regard.
[ABSTRACT]
[FULL TEXT]
[PDF]
[CITATIONS]
[PubMed]
6,956
396
6
LETTERS TO EDITOR
Cytomegalovirus polyradiculopathy: A rare neurological manifestation of acquired immunodeficiency syndrome
Anant Mohan, Duncan Smith-Rohrberg, M Sethu, SK Sharma
October-December 2008, 56(4):493-494
DOI
:10.4103/0028-3886.44826
PMID
:19127057
[FULL TEXT]
[PDF]
[CITATIONS]
[PubMed]
6,935
145
4
ORIGINAL ARTICLES
Proprioceptive loss in leprous neuropathy: A study of 19 patients
Satish V Khadilkar, Rajesh Benny, Prasanna S Kasegaonkar
October-December 2008, 56(4):450-455
DOI
:10.4103/0028-3886.44824
PMID
:19127041
Background:
Leprosy presents commonly with mononeuritis multiplex, affecting mainly the exteroceptive sensations. Neuropathy with a significant afferent large fiber element is considered to be an uncommon manifestation of leprous neuropathy.
Aims:
To evaluate the clinical and neurophysiologic aspects of a subset of patients with leprous neuropathy having clinical proprioceptive loss.
Settings and Design:
Prospective study of patients with a diagnosis of peripheral neuropathy secondary to leprosy having proprioceptive loss.
Materials and Methods:
Consecutive patients seen during a two-year period (2004 and 2005) diagnosed to have leprous neuropathy with proprioceptive abnormalities on clinical examination were included. The diagnosis of leprosy was achieved by clinical features along with positive skin biopsy, split skin smears or nerve biopsy. Their clinical and electrophysiological characteristics were studied.
Statistical Methods
: The results were analyzed using Chi-Square test. Values less than 0.05 were considered to be statistically significant
. Results and Conclusions:
We observed predominance (68.42%) of multibacillary of leprosy. Symmetrical neuropathies outnumbered mononeuritis multiplex (12:7). The pan sensory neuropathy had a mean duration of 24.32 months, but sometimes appeared early in the course of the disease. Areflexia and electrophysiological evidence of proximal affection was common, reflecting proximal spread of neuropathic process. Such patients have a higher incidence of developing deformities and ulcerations and they represent a vulnerable subset of patients with leprosy.
[ABSTRACT]
[FULL TEXT]
[PDF]
[CITATIONS]
[PubMed]
6,104
359
7
CASE REPORTS
A case of tactile agnosia with a lesion restricted to the post-central gyrus
Bruno Estanol, Jose Fidel Baizabal-Carvallo, Horacio Senties-Madrid
October-December 2008, 56(4):471-473
DOI
:10.4103/0028-3886.44829
PMID
:19127044
Tactile agnosia has been described after lesions of the primary sensory cortex but the exact location and extension of those lesions is not clear. We report the clinical features and imaging findings in a patient with an acute ischemic stroke restricted to the primary sensory area (S1). A 73-year-old man had a sudden onset of a left alien hand, without left hemiparesis. Neurological examination showed intact primary sensory functions, but impaired recognition of shape, size (macrogeometrical) and texture (microgeometrical) of objects; damage confined to the post-central gyrus, sparing the posterior parietal cortex was demonstrated on MRI. An embolic occlusion of the anterior parietal artery was suspected as mechanism of stroke. Tactile agnosia with impaired microgeometrical and macrogeometrical features' recognition can result from a single lesion in the primary sensory cortex (S1) in the right parietal hemisphere, sparing other regions of the cerebral cortex which presumably participate in tactile object recognition.
[ABSTRACT]
[FULL TEXT]
[PDF]
[CITATIONS]
[PubMed]
6,135
219
5
ORIGINAL ARTICLES
Epidermal growth factor receptor and proliferating cell nuclear antigen in astrocytomas
Arpan K Maiti, Keya Ghosh, Uttara Chatterjee, Sasanka Chakrobarti, Sandip Chatterjee, Samik Basu
October-December 2008, 56(4):456-462
DOI
:10.4103/0028-3886.44827
PMID
:19127042
Aims:
The involvement of various growth factors, growth factor receptors and proliferative markers in the molecular pathogenesis of astrocytic neoplasms are being studied extensively. Epidermal Growth Factor Receptor (EGFR) gene overexpression occurs in nearly 50% of cases of glioblastoma. Since EGFR and proliferating cell nuclear antigen (PCNA) are involved in mitogenic signal transduction and cellular proliferation pathway, we have studied the correlation between the expression of EGFR and PCNA labeling index in astrocytic tumors.
Materials and Methods:
We investigated the immunohistochemical expression of EGFR and PCNA using the appropriate monoclonal antibodies in 40 cases of astrocytic tumors of which 21 cases were glioblastoma, eight cases were Grade III or anaplastic astrocytomas and six cases were Grade II or diffuse astrocytomas and five cases were Grade I or pilocytic astrocytomas.
Results:
Both the EGFR expression and PCNA labeling index increase with increasing grades of astrocytomas with a significantly high percentage of cells showing positive staining for both EGFR and PCNA in GBM and Grade III astrocytomas compared to Grade II astrocytomas. The expression levels of both EGFR and PCNA were low in Grade I or pilocytic astrocytomas.
Conclusions:
A significant correlation was found between EGFR overexpression and PCNA labeling index in Grade III and Grade II astrocytomas and glioblastoma. These suggest that the tumor proliferation, at least in higher grades of astrocytomas is dependent in some measure on EGF and EGFR-related signaling pathways.
[ABSTRACT]
[FULL TEXT]
[PDF]
[CITATIONS]
[PubMed]
5,850
292
14
LETTERS TO EDITOR
Anesthetic management of a patient with
Huntington's chorea
Kad Nandita, Lal Jatin, Hooda Sarla
October-December 2008, 56(4):486-487
DOI
:10.4103/0028-3886.44818
PMID
:19127052
[FULL TEXT]
[PDF]
[CITATIONS]
[PubMed]
5,789
142
3
Duplication of the common carotid artery and the ipsilateral vertebral artery with a fenestration of the contralateral common carotid artery
Simon Harnier, Andreas Harzheim, Volker Limmroth, Reinhold Horz, Jens Kuhn
October-December 2008, 56(4):491-493
DOI
:10.4103/0028-3886.44825
PMID
:19127056
[FULL TEXT]
[PDF]
[CITATIONS]
[PubMed]
5,419
126
10
OBITUARIES
Professor Yoshio Suzuki (1947-2008)
Sanjay Behari, Kiyoshi Saito, Yoko Kato
October-December 2008, 56(4):499-500
DOI
:10.4103/0028-3886.44809
PMID
:19127060
[FULL TEXT]
[PDF]
[PubMed]
4,666
153
-
LETTERS TO EDITOR
Familial mirror movements over five generations
Naser Sharafaddinzadeh, Reza Bavarsad, Mahyar Yousefkhah, Armaghan Moravej Aleali
October-December 2008, 56(4):482-483
DOI
:10.4103/0028-3886.44813
PMID
:19127048
[FULL TEXT]
[PDF]
[CITATIONS]
[PubMed]
4,610
138
10
ORIGINAL ARTICLES
Central motor conduction in brachial monomelic amyotrophy
Pramod K Pal, Nalini Atchayaram, Gaurav Goel, Ebenezer Beulah
October-December 2008, 56(4):438-443
DOI
:10.4103/0028-3886.44820
PMID
:19127039
Background:
Prevalence of subclinical involvement of motor pathways in clinically diagnosed Brachial Monomelic Amyotrophy (BMMA) is unknown.
Aims:
To determine the prevalence of subclinical involvement of central motor pathways in BMMA using transcranial magnetic stimulation.
Setting and Design:
Prospective case-control study.
Materials and Methods:
Central motor conduction time (CMCT) was determined by 'F' wave method using figure-of-eight coil attached to Magstim 200 stimulator, in 17 patients with BMMA. Motor evoked potentials were recorded from first dorsal interosseous of the affected (AFF) and unaffected upper limbs (UNAFF) at rest and during partial contraction. Comparison was made with data from 10 healthy controls (CTRL).
Statistical Analysis:
Descriptive analysis and Analysis of Variance (ANOVA).
Results:
Compared to controls, the mean CMCT of AFF was significantly prolonged, both at rest and contraction: (a) Rest: AFF-6.68±1.78 ms, UNAFF-6.36±1.16 ms, CTRL-5.71±1.02 ms; Fisher's PLSD for AFF vs. CTRL:
P
=0.037, (b) Contraction: AFF-5.78±1.62 ms, UAFF - 4.86±1.38 ms, CTRL-4.06±0.80 ms; Fisher's PLSD for AFF vs. CTRL;
P
=0.0002, AFF vs. UNAFF-
P
=0.044). Prolonged CMCT (>mean+2SD of controls) was observed in 29.4% of AFF and 6.25% of UNAFF at rest, and in 47.1% and 23.5% respectively during contraction.
Conclusions:
Dysfunction of central motor pathways was observed in both affected and unaffected upper limbs of some patients with BMMA of upper limbs. The dysfunction was more pronounced during voluntary contraction. A larger study is needed to validate the significance of these findings.
[ABSTRACT]
[FULL TEXT]
[PDF]
[CITATIONS]
[PubMed]
4,557
180
5
NEUROIMAGES
Lhermitte-Duclos disease
Anjamparuthikal A Haris, Sadanandavalli R Chandra, Byju Peethambaran
October-December 2008, 56(4):495-496
DOI
:10.4103/0028-3886.44811
PMID
:19127058
[FULL TEXT]
[PDF]
[CITATIONS]
[PubMed]
4,418
276
7
CASE REPORTS
Congenital irreducible atlantoaxial dislocation associated with cervical intramedullary astrocytoma causing progressive spastic quadriparesis
Anooj Chatley, Awadesh K Jaiswal, Manoj Jain, Sanjay Behari
October-December 2008, 56(4):477-479
DOI
:10.4103/0028-3886.44831
PMID
:19127046
Simultaneous presence of congenital irreducible atlantoaxial dislocation (AAD) and cervical intramedullary astrocytoma has not been previously described and may cause disabling myelopathy. This 55-year-old lady presented with suboccipital pain, spastic quadriparesis, Lhermitte's phenomenon and sphincteric disturbances. Lateral radiographs and magnetic resonance imaging showed irreducible AAD, occipitalized atlas, C2-3 fusion, and,an intramedullary tumor from C2-5 level iso-to-hypointense, non-enhancing, except in a small segment in the dorsal C2 level. A suboccipital craniectomy with C2-5 laminectomy revealed a greyish-white tenacious tumor. The tumor was decompressed using a C2-5 midline myelotomy and duroplasty. An occipitocervical lateral mass fixation was performed. Histopathology revealed a low-grade astrocytoma. At three-month follow-up, her spasticity had decreased and quadriparesis and sphincteric disturbances were persisting. Postoperative lateral radiographs and intrathecal contrast CT scan showed a stable occipitocervical construct. Thus, the suboccipital craniectomy and laminectomy with midline myelotomy and duroplasty facilitated space for progressively expanding intramedullary astrocytoma with irreducible AAD; the lateral mass fixation provided stability at the craniovertebral junction.
[ABSTRACT]
[FULL TEXT]
[PDF]
[CITATIONS]
[PubMed]
4,231
178
1
EDITORIAL
Integrity, immunity, reactivity, restorativity: Biolessons off brain abscess
Manu Kothari, Atul Goel
October-December 2008, 56(4):397-398
DOI
:10.4103/0028-3886.44807
PMID
:19127032
[FULL TEXT]
[PDF]
[CITATIONS]
[PubMed]
4,025
342
3
NEUROIMAGES
Monostotic fibrous dysplasia of the C4 cervical spine
M Sambasivan, P Sanalkumar, S Mahesh, K Rajasekharan Nair, Abeed Basheer
October-December 2008, 56(4):497-498
DOI
:10.4103/0028-3886.44810
PMID
:19127059
[FULL TEXT]
[PDF]
[CITATIONS]
[PubMed]
3,987
151
6
LETTERS TO EDITOR
MRI diagnosis of neurolymphomatosis of the brachial plexus
Arti Chaturvedi, JP Singh, Vikas Rastogi
October-December 2008, 56(4):485-486
DOI
:10.4103/0028-3886.44817
PMID
:19127051
[FULL TEXT]
[PDF]
[CITATIONS]
[PubMed]
3,898
143
3
VIEWPOINT
Foramen-fallacy: Descriptive-delusion
Manu Kothari, Atul Goel
October-December 2008, 56(4):480-481
DOI
:10.4103/0028-3886.44832
PMID
:19127047
[FULL TEXT]
[PDF]
[CITATIONS]
[PubMed]
3,539
119
3
LETTERS TO EDITOR
Infraoptic azygous anterior cerebral artery
Vipul Gupta, Manish Chugh, Sandeep Vaishya
October-December 2008, 56(4):487-488
DOI
:10.4103/0028-3886.44819
PMID
:19127053
[FULL TEXT]
[PDF]
[CITATIONS]
[PubMed]
3,367
115
6
Endovascular management of a refractory traumatic aneurysm of the internal carotid artery using a covered stent graft
Balaji S Pai, Uday Limaye, Ravi G Varma
October-December 2008, 56(4):488-500
DOI
:10.4103/0028-3886.44821
PMID
:19127054
[FULL TEXT]
[PDF]
[CITATIONS]
[PubMed]
3,308
153
4
Unilobar multiple cerebral hydatid cyst: A rare disease
Milind P Joshi, Rahul J Potode, Anil M Bhole, Sudhakar R Joharapurkar
October-December 2008, 56(4):483-484
DOI
:10.4103/0028-3886.44815
PMID
:19127049
[FULL TEXT]
[PDF]
[CITATIONS]
[PubMed]
3,196
180
2
Cushing's disease
presenting as an intracerebral hemorrhage
Abhidha H Shah, Atul Goel
October-December 2008, 56(4):490-491
DOI
:10.4103/0028-3886.44822
PMID
:19127055
[FULL TEXT]
[PDF]
[CITATIONS]
[PubMed]
3,100
139
2
Site Map
|
Home
|
Contact Us
|
Advertise With Us
|
Feedback
|
Copyright and Disclaimer
|
Privacy Notice
Online since 20
th
March '04
Published by Wolters Kluwer -
Medknow
CookieĀ Settings