|Year : 2021 | Volume
| Issue : 4 | Page : 1142-
Bone Mineral Density and Serum Vitamin D Status in Parkinson's Disease: Are the Stage and Clinical Features of the Disease Important?
Mahmood Dhahir Al-Mendalawi
Department of Paediatrics, Al-Kindy College of Medicine, University of Baghdad, Baghdad, Iraq
Mahmood Dhahir Al-Mendalawi
P.O. Box 55302, Baghdad Post Office, Baghdad
|How to cite this article:|
Al-Mendalawi MD. Bone Mineral Density and Serum Vitamin D Status in Parkinson's Disease: Are the Stage and Clinical Features of the Disease Important?.Neurol India 2021;69:1142-1142
|How to cite this URL:|
Al-Mendalawi MD. Bone Mineral Density and Serum Vitamin D Status in Parkinson's Disease: Are the Stage and Clinical Features of the Disease Important?. Neurol India [serial online] 2021 [cited 2021 Oct 25 ];69:1142-1142
Available from: https://www.neurologyindia.com/text.asp?2021/69/4/1142/325366
It is worthy to comment on the interesting case-control study by Ozturk et al. published in March–April 2020 issue of the Neurology India. On employing dual-energy X-ray absorptiometry (DEXA), Ozturk et al. found that lumbar and femoral bone mineral density (BMD) levels were lower significantly in Turkish patients with Parkinson's disease (PD) in comparison with controls. The low BMD values were detected in the early stages of the PD (stage 1 and 1.5) and were marked by the progress of the disease. There was a negative correlation between BMD and the clinical pictures of the PD. Ozturk et al. recommended that all PD patients must be screened for developing osteoporosis in the early stages of the disease. Besides a few study limitations mentioned by Ozturk et al., I presume that the following methodological limitation is relevant. It is obvious that BMD reference values (BMDRV) are needed to interpret BMD values estimated by DEXA. Since BMDRV is determined by different factors, notably age, gender, race, weight, pubertal stage, and socioeconomic class,, normative BMDRV has been formulated for certain populations to be utilized in the researches centers and clinical settings. Turkey is among pioneer countries that have already generated their BMDRV. Regrettably, Ozturk et al. didn't address in the study methodology which BMDRV they employed to evaluate the calculated BMD levels. Hence, this limitation might bring into question the correctness of the study findings and recommendations addressed by Ozturk et al.
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