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ORIGINAL ARTICLE
Year : 2021  |  Volume : 69  |  Issue : 2  |  Page : 354--359

Nonconvulsive Status Epilepticus in Metabolic Encephalopathy in Indonesia Referral Hospital

Fitri Octaviana1, Andriani P Bestari1, Anastasia M Loho1, Luh A Indrawati1, Winnugroho Wiratman1, Mohammad Kurniawan1, Adhrie Sugiarto2, Astri Budikayanti1 
1 Department of Neurology, Faculty of Medicine, Universitas Indonesia/Cipto Mangunkusumo General Hospital, Jakarta, Indonesia
2 Department of Anesthesiology and Intensive Therapy, Faculty of Medicine, Universitas Indonesia/Cipto Mangunkusumo General Hospital, Jakarta, Indonesia

Correspondence Address:
Fitri Octaviana
Department of Neurology, Faculty of Medicine, Universitas Indonesia/Cipto Mangunkusumo General Hospital, Jakarta
Indonesia

Background: Nonconvulsive status epilepticus (NCSE) is often underdiagnosed in patients with metabolic encephalopathy (ME). The diagnosis of ME should be made specifically to recognize the underlying etiology. Delay in seizure identification and making a diagnosis of NCSE contributed to the poor outcome. Objective: This study aimed to find the incidence and outcome of NCSE in patients with ME. Methods and Material: This was an observational prospective cross-sectional study in patients with ME in emergency and critical care units in Cipto Mangunkusumo General Hospital. The diagnosis of NCSE was based on EEG using Salzburg Criteria for Nonconvulsive Status Epilepticus (SCNC). The outcome was assessed within 30 days after the NCSE diagnosis has been made. Results: A total of 50 patients with ME were involved in this study. NCSE was confirmed in 32 subjects (64%). The most common etiology of ME was sepsis (58%). The mortality rate in the NCSE and non-NCSE group was 40.6% vs 44.4%. Multiple aetiologies were risk factors to poor outcome in the NCSE group. Conclusions: The incidence of NCSE among patients with ME at our hospital was high. Despite the anti-epileptic treatment of the NCSE group, the underlying cause of ME is still the main factor that affected the outcome. Therefore, aggressive treatment of anti-epileptic drug (AED) should be very carefully considered knowing the possible side-effect that might worsen the outcome of patients with ME.


How to cite this article:
Octaviana F, Bestari AP, Loho AM, Indrawati LA, Wiratman W, Kurniawan M, Sugiarto A, Budikayanti A. Nonconvulsive Status Epilepticus in Metabolic Encephalopathy in Indonesia Referral Hospital.Neurol India 2021;69:354-359


How to cite this URL:
Octaviana F, Bestari AP, Loho AM, Indrawati LA, Wiratman W, Kurniawan M, Sugiarto A, Budikayanti A. Nonconvulsive Status Epilepticus in Metabolic Encephalopathy in Indonesia Referral Hospital. Neurol India [serial online] 2021 [cited 2021 Jun 13 ];69:354-359
Available from: https://www.neurologyindia.com/article.asp?issn=0028-3886;year=2021;volume=69;issue=2;spage=354;epage=359;aulast=Octaviana;type=0