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CASE REPORT
Year : 2004  |  Volume : 52  |  Issue : 1  |  Page : 99--101

Cerebral autosomal dominant arteriopathy with subcortical infarcts and leucoencephalopathy (CADASIL): A case report with review of literature

JK Gurumukhani, M Ursekar, BS Singhal 
 Bombay Hospital Institute of Medical Sciences, 12, New Marine Lines, Mumbai - 400020, India

Correspondence Address:
B S Singhal
Department of Neurolog, Bombay Hospital Institute of Medical Sciences, 12, New Marine Lines, Mumbai - 400020
India

Cerebral autosomal dominant arteriopathy with subcortical infarcts and leucoencephalopathy (CADASIL) is an inherited arterial disease, commonly overlooked or misdiagnosed. We report a case of CADASIL in a 51 years old woman who presented with progressive subcortical dementia, recurrent ischemic events and seizures in the absence of known vascular risk factors of five years’ duration. Her mother had a history of similar illness. Magnetic resonance imaging (MRI) of brain revealed subcortical and deep white matter hyperintense lesions within the cerebral white matter on T2-weighted images. DNA mutation of Notch 3 gene confirmed the diagnosis of CADASIL.


How to cite this article:
Gurumukhani J K, Ursekar M, Singhal B S. Cerebral autosomal dominant arteriopathy with subcortical infarcts and leucoencephalopathy (CADASIL): A case report with review of literature.Neurol India 2004;52:99-101


How to cite this URL:
Gurumukhani J K, Ursekar M, Singhal B S. Cerebral autosomal dominant arteriopathy with subcortical infarcts and leucoencephalopathy (CADASIL): A case report with review of literature. Neurol India [serial online] 2004 [cited 2021 Sep 24 ];52:99-101
Available from: https://www.neurologyindia.com/article.asp?issn=0028-3886;year=2004;volume=52;issue=1;spage=99;epage=101;aulast=Gurumukhani;type=0