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Year : 2004  |  Volume : 52  |  Issue : 1  |  Page : 133-

Sphenoid wing meningioma presenting as hemi-parkinsonism: Case report

KC Shah, V Rajshekhar 
 Department of Neurological Sciences, Christian Medical College Hospital, Vellore, India

Correspondence Address:
K C Shah
Department of Neurological Sciences, Christian Medical College Hospital, Vellore
India




How to cite this article:
Shah K C, Rajshekhar V. Sphenoid wing meningioma presenting as hemi-parkinsonism: Case report.Neurol India 2004;52:133-133


How to cite this URL:
Shah K C, Rajshekhar V. Sphenoid wing meningioma presenting as hemi-parkinsonism: Case report. Neurol India [serial online] 2004 [cited 2021 Oct 25 ];52:133-133
Available from: https://www.neurologyindia.com/text.asp?2004/52/1/133/6734


Full Text

Sir,

Parkinson's disease (PD) has infrequently been described in association with intracranial tumors.[1],[2],[3],[4] We describe a patient who had a sphenoid wing meningioma and presented with hemi-parkinsonism. Parkinsonism was completely relieved after tumor resection.

A 54-year-old woman presented with a 2-month history of tremor, particularly at rest, in the left upper limb and 2 episodes of generalized seizures. Examination revealed a masked facies, rest tremor in the left hand with a postural tremor of small amplitude, cog- wheel rigidity at the left wrist and elbow and loss of dexterity due to bradykinesia. Fundus showed bilateral papilledema. Gait was normal but slow and left arm swing was diminished. Rest of the neurological examination revealed no abnormality. MRI of the brain showed a large homogenous dural-based mass along the right medial sphenoidal wing with significant perilesional edema and midline shift [Figure:1]. She underwent right fronto-temporal craniotomy and near-total excision of the tumor. Postoperatively her tremor and rigidity in the left upper limb disappeared completely. Histologically, the tumor was a meningioma.

The basal ganglia play a major role in the control of posture and movement. Intrinsic basal ganglionic and thalamic lesions as well as extrinsic compressive lesions have been reported to cause Parkinsonism-like syndrome. Parkinsonism is produced more often by external masses impinging on the basal ganglia than by intrinsic infiltrating lesions. Gliomas, meningiomas, metastatic tumors and even chronic subdural hematoma have been reported to produce symptoms of Parkinsonism.[2],[5]

Direct mechanical pressure and/or torsion of the basal ganglia by a tumor might cause dysfunction of these nuclei. The other proposed mechanism is midbrain compression from upward or downward transtentorial herniation.[3] Such herniation may result in the impairment of blood flow to the basal ganglia via the posterior cerebral artery, leading to ischemia of the subthalamic nuclei. In intrinsic tumors, the basal ganglia and thalamus are involved primarily by the tumor, which may lead to internal compression of neurons or pathways.

An intracranial mass as a cause of PD might be missed, especially in elderly patients. Associated symptoms of increased intracranial pressure, focal motor or sensory deficits or seizures (as in our patient) can assist in the diagnosis.

References

1Polyzoidis KS, McQueen JD, Rajput AH, MacFadyen DJ. Parkinsonism as a manifestation of brain tumour. Surg Neurol 1985;23:59-63.
2Straube A, Sigel K. Parkinsonian syndrome caused by a tumour of the left supplementary motor area. J Neurol Neurosurg Psychiaty 1988;51:730-1.
3Oliver L. Parkinsonism due to midbrain compression. Lancet 1959;2:817-9.
4Wakai S, Nakamura K, Nilzaki K, Nagai M, Mishizawa T, Yokoyama S, Katayama S. Meningioma of the anterior third ventricle presenting with parkinsonism. Surg Neurol 1984;21:88-92.
5Sandyk R, Kahn I. Parkinsonism due to subdural haematoma: case report. J Neurosurg 1983;58:298-9.