Atormac
briv
Neurology India
menu-bar5 Open access journal indexed with Index Medicus
  Users online: 238  
 Home | Login 
About Editorial board Articlesmenu-bullet NSI Publicationsmenu-bullet Search Instructions Online Submission Subscribe Videos Etcetera Contact
  Navigate Here 
 Search
 
  
 Resource Links
    Similar in PUBMED
    Article in PDF (638 KB)
    Citation Manager
    Access Statistics
    Reader Comments
    Email Alert *
    Add to My List *
* Registration required (free)  

 
  In this Article
   References
   Article Figures

 Article Access Statistics
    Viewed186    
    Printed8    
    Emailed0    
    PDF Downloaded8    
    Comments [Add]    

Recommend this journal

 


 
Table of Contents    
NEUROIMAGE
Year : 2021  |  Volume : 69  |  Issue : 5  |  Page : 1492-1493

Intratumoral Hemorrhage in Vestibular Schwannoma: An Unusual but Alarming Clinical Entity


Department of Neurosurgery, Kasturba Medical College, Manipal, Manipal Academy of Higher Education (MAHE), Manipal, Karnataka, India

Date of Submission26-Jun-2020
Date of Decision04-Jul-2020
Date of Acceptance15-Jul-2020
Date of Web Publication30-Oct-2021

Correspondence Address:
Raghavendra Nayak
Department of Neurosurgery, Kasturba Medical College, Manipal, MAHE, Manipal, Karnataka
India
Login to access the Email id

Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0028-3886.329608

Rights and Permissions



How to cite this article:
Onkarappa S, Nayak R, Menon G. Intratumoral Hemorrhage in Vestibular Schwannoma: An Unusual but Alarming Clinical Entity. Neurol India 2021;69:1492-3

How to cite this URL:
Onkarappa S, Nayak R, Menon G. Intratumoral Hemorrhage in Vestibular Schwannoma: An Unusual but Alarming Clinical Entity. Neurol India [serial online] 2021 [cited 2021 Nov 28];69:1492-3. Available from: https://www.neurologyindia.com/text.asp?2021/69/5/1492/329608




Presentation of brain tumors with intratumoral hemorrhage occurs in about 1.4–10% of cases; usually in metastatic brain tumors, aggressive high-grade gliomas, melanomas, and even in choroid plexus papilloma.[1] But the hemorrhage in the vestibular schwannoma is unusual and happens in less than 1% of cases.[2]

A 48-year-old lady with a 3-year history of left-side decreased hearing, presented to us with giddiness, vomiting, and facial asymmetry of two days. On examination, she had a left lower motor facial palsy (House-Brackmann grade 4) and severe left cerebellar signs. Magnetic resonance imaging of the brain was done which showed an extra-axial well-defined mass in the left cerebellar pontine cistern with a cone-like protrusion into the widened internal auditory canal. It was hypointense on T1 and heterogeneously hyperintense on both T2 and fluid-attenuated inversion recovery. There was a heterogeneous enhancement of gadolinium post-contrast. It showed an intense focus of blooming on susceptibility-weighted images indicating the intratumoral hemorrhage [Figure 1]. Our diagnosis was vestibular schwannoma with Intra tumoral hemorrhage (ITH) although the exophytic brainstem glioma and metastasis were also considered in the differential.
Figure 1: Magnetic resonance imaging showing T1 hypointense (a), T2, and fluid-attenuated-inversion-recovery (FLAIR) heterogeneously hyperintense (b and c), heterogeneously contrast-enhancing (d) mass in the cerebellar pontine cistern with intratumoral hemorrhage as evidence by susceptibility-weighted image (SWI) blooming (e). No evidence of diffusion restriction noted. The lesion was noted to cause mass effect seen in the form of buckling of the adjacent left cerebellar hemisphere, brainstem, and compression of the fourth ventricle. Postoperative computer tomography showing complete excision of the tumor (f)

Click here to view


We did a left retrosigmoid suboccipital craniotomy and complete excision of the tumor. Intraoperatively tumor had both organized and liquid clots. Histopathology was suggestive of schwannoma.

The mechanism of hemorrhage in the tumor is still poorly understood. The proliferation of thin-walled, dilated, and sinusoidal vasculature could be blamed for.[3] As the occurrence of ITH is rare, causes are always debatable. Likely risk factors include large tumor size (>2 cm), Cystic tumor, hypertension, physical exertion, anticoagulation therapy rapid tumor growth, and increased tumor vascularity.[4] A high correlation has been observed between hypertension and ITH.[5] Clinical outcome of ITH is substantially poor. Increased death rates (10%) and higher facial nerve weakness (31.3%) have been observed in Vestibular Shwannoma (VS) with ITH when compared to the VS without any hemorrhage (mortality: 0.2% and facial weakness: 6%).[3]

Declaration of patient consent

The authors certify that they have obtained all appropriate patient consent forms. In the form, the patient(s) has/have given his/her/their consent for his/her/their images and other clinical information to be reported in the journal. The patients understand that their names and initials will not be published and due efforts will be made to conceal their identity, but anonymity cannot be guaranteed.

Financial support and sponsorship

Nil.

Conflicts of interest

There are no conflicts of interest.



 
  References Top

1.
Diyora B, Sharma A, Badhe P, Nayak N. Hemorrhage in acoustic neurinoma. Neurology India 2010;58:329-30.  Back to cited text no. 1
    
2.
Carlson ML, Tombers NM, Driscoll CL, Van Gompel JJ, Lane JI, Raghunathan A, et al. Clinically significant intratumoral hemorrhage in patients with vestibular schwannoma. Laryngoscope 2017;127:1420-6.  Back to cited text no. 2
    
3.
Niknafs YS, Wang AC, Than KD, Etame AB, Thompson BG, Sullivan SE. Hemorrhagic vestibular schwannoma: Review of the literature. World Neurosurg 2014;82:751-6.  Back to cited text no. 3
    
4.
Dehdashti AR, Kiehl TR, Guha A. Vestibular Schwannomas presenting with haemorrhage: Clinical presentation and histopathological evaluation of an unusual entity. Br J Neurosurgery 2009;23:431-6.  Back to cited text no. 4
    
5.
Yang X, Liu J, Zhang Y, Richard SA. Tumor-associated hemorrhage in patients with vestibular schwannoma. Acta Neurochir (Wien) 2018;160:1563-9.  Back to cited text no. 5
    


    Figures

  [Figure 1]



 

Top
Print this article  Email this article
   
Online since 20th March '04
Published by Wolters Kluwer - Medknow