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|Year : 2021 | Volume
| Issue : 5 | Page : 1489
Half Wine Glass Appearance in Early Primary Lateral Sclerosis
Jidhin Raj1, Jacob George1, AA Harris1, Neethu Suresh1, Gourishankar2
1 Department of Neurology, Government Medical College, Kottayam, Kerala, India
2 Department of Radiology, Government Medical College, Kottayam, Kerala, India
|Date of Submission||25-Nov-2019|
|Date of Decision||27-Nov-2019|
|Date of Acceptance||11-Jul-2020|
|Date of Web Publication||30-Oct-2021|
Department of Neurology, Government Medical College, Kottayam - 686 008, Kerala
Source of Support: None, Conflict of Interest: None
|How to cite this article:|
Raj J, George J, Harris A A, Suresh N, Gourishankar. Half Wine Glass Appearance in Early Primary Lateral Sclerosis. Neurol India 2021;69:1489
A 42-year-old gentleman presented with progressive loss of dexterity and pyramidal weakness of right upper limb for three months duration. There was no cognitive decline, tongue/limb muscle atrophy, fasciculation or sensory loss. Our patient fulfilled the criteria for primary lateral sclerosis except the duration criteria of three years.
Wine glass appearance has been previously described in primary lateral sclerosis with white matter confluent symmetrical hyperintensities of both corticospinal tracts in the coronal section. The hyperintensities of the corticospinal tract of a single side may be considered as an early sign of primary lateral sclerosis [Figure 1].
|Figure 1: MRI Brain T2 FLAIR coronal section shows left corticospinal tract hyperintensity. Right corticospinal tract appears normal|
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Declaration of patient consent
The authors certify that they have obtained all appropriate patient consent forms. In the form, the patient(s) has/have given his/her/their consent for his/her/their images and other clinical information to be reported in the journal. The patients understand that their names and initials will not be published and due efforts will be made to conceal their identity, but anonymity cannot be guaranteed.
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Conflicts of interest
There are no conflicts of interest.
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Pringle CE, Hudson AJ, Munoz DG, Kiernan JA, Brown WF, Ebers GC. Primary lateral sclerosis. Clinical features, neuropathology and diagnostic criteria. Brain 1992;115:495-520.
Kuruvilla A, Joseph S. 'Wine Glass' appearance: A unique MRI observation in a case of primary lateral sclerosis. Neurol India 2002;50:306-9.
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