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Year : 2020  |  Volume : 68  |  Issue : 8  |  Page : 163--169

Fundamentals of Neuromodulation and Pathophysiology of Neural Networks in Health and Disease


1 Department of Neurology, Rockefeller Neuroscience Institute, West Virginia University, 33 Medical Center Drive, Morgantown, WV, USA
2 Department of Neurosurgery, Rockefeller Neuroscience Institute, West Virginia University, 33 Medical Center Drive, Morgantown, WV, USA

Correspondence Address:
Dr. Richa Tripathi
Department of Neurology, Rockefeller Neuroscience Institute, West Virginia University, 33 Medical Center Drive, Morgantown, WV- 26505
USA
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0028-3886.302463

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Neuromodulation involves altering neuronal circuitry and subsequent physiological changes with the aim to ameliorate neurological symptoms. Over the years several techniques have been used to obtain neuromodulatory effects for treatment of conditions including Parkinson disease, essential tremor, dystonia or seizures. We provide brief description of the various therapeutics that have been used and mechanisms involved in pathophysiology of these disorders as well as the therapeutic mechanisms of the treatment modalities.






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Online since 20th March '04
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