Neurology India
menu-bar5 Open access journal indexed with Index Medicus
  Users online: 4330  
 Home | Login 
About Editorial board Articlesmenu-bullet NSI Publicationsmenu-bullet Search Instructions Online Submission Subscribe Videos Etcetera Contact
  Navigate Here 
 »   Next article
 »   Previous article
 »   Table of Contents

 Resource Links
 »   Similar in PUBMED
 »  Search Pubmed for
 »  Search in Google Scholar for
 »Related articles
 »   Citation Manager
 »   Access Statistics
 »   Reader Comments
 »   Email Alert *
 »   Add to My List *
 * Requires registration (Free)

 Article Access Statistics
    PDF Downloaded11    
    Comments [Add]    

Recommend this journal


Year : 2020  |  Volume : 68  |  Issue : 6  |  Page : 1389--1393

Incidence Study of Epilepsy using the ILAE 2017 Classification of Epilepsies in a Cohort of School Children Accessing Education in Government Primary Schools in South India

Department of Neurology, The Institute of Neurological Sciences, *CARE Hospital and NICE Hospital and NICE Foundation, Hyderabad, Telangana, India

Correspondence Address:
Dr. Jagarlapudi M. K Murthy
Chief of Neurology, The Institute of Neurological Sciences, CARE Hospitals, Care Outpatient Center, Road No: 10, Banjara Hills, Hyderabad–500 034, Telangana
Login to access the Email id

Source of Support: None, Conflict of Interest: None

DOI: 10.4103/0028-3886.304099

Rights and Permissions

Background: Recently, the International League Against Epilepsy (ILAE) has proposed new classification schemes for seizures and epilepsy. The applicability of these classification schemes has not been studied in resource-poor countries. Aim: To determine the incidences of epilepsies in a cohort of school children using the ILAE 2017 classification of epilepsies. Materials and Methods: The study cohort included 7,408 school going children [age range 5–15 years]. They were followed for new-onset unprovoked seizure and seizure recurrence through first grade to fifth grade. The data collected during the first visit included clinical details including details of seizure semiology. All children had EEG and contrast CT scan. All these data were used to classify seizure type and epilepsy using ILAE classification schemes. The ILAE 2014 epilepsy definition was used to diagnose epilepsy. The average annual incidence rates (AAIR) and 95% confidence intervals (CI) were calculated for epilepsies by onset and by etiology. Results: The AAIR of epilepsy was 57.85 (95% CI 39.0–82.6) per 100,000 population. The AAIRs per 100,000 for different epilepsies by mode of onset were focal epilepsies 25.07 (95% CI 13.35–42.87); generalized epilepsies 13.5 (95% CI 5.43–27.8); and unknown onset epilepsies 19.28 (95% CI 9.25–35.46). The AAIRs per 100,000 of epilepsies by etiology were focal genetic epilepsies 7.71 (95% CI 2.1–19.75); genetic generalized epilepsies 13.5 (95% CI 5.43–27.8); and epilepsies due to structural cause 17.36 (95% CI 9.25–35.46). The lesional epilepsies seen in this cohort were geographically specific to resource-poor countries. The AAIR of epilepsy due to calcific neurocysticercosis (cNCC) was 9.64 (95% CI 3.1–22.5) per 100,000. Conclusions: This study demonstrates that the ILAE 2017 classification of epilepsies can be applied in resource-poor countries with limited workup. Lesional epilepsies seen in this study is geographically specific to resource-poor countries.


Print this article     Email this article

Online since 20th March '04
Published by Wolters Kluwer - Medknow