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Year : 2019  |  Volume : 67  |  Issue : 1  |  Page : 229--234

Construction of Indian human brain atlas

1 Center for Visual Information Technology, International Institute of Information Technology (IIIT), Hyderabad, Telangana, India
2 Center for Visual Information Technology, International Institute of Information Technology (IIIT), Hyderabad, Telangana; Probabilistic Vision Group, Centre for Intelligent Machines, Department of electrical and Computer Engineering, McGill University, Montreal, QC, Canada
3 Department of Imaging Sciences and Interventional Radiology, Sree Chitra Tirunal Institute for Medical Sciences and Technology, Thiruvananthapuram, Kerala, India

Correspondence Address:
Dr. Jayanthi Sivaswamy
Center for Visual Information Technology, IIIT, Hyderabad, Telangana
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/0028-3886.253639

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Context: A brain magnetic resonanace imaging (MRI) atlas plays an important role in many neuroimage analysis tasks as it provides an atlas with a standard coordinate system which is needed for spatial normalization of a brain MRI. Ideally, this atlas should be as near to the average brain of the population being studied as possible. Aims: The aim of this study is to construct and validate the Indian brain MRI atlas of young Indian population and the corresponding structure probability maps. Settings and Design: This was a population-specific atlas generation and validation process. Materials and Methods: 100 young healthy adults (M/F = 50/50), aged 21–30 years, were recruited for the study. Three different 1.5-T scanners were used for image acquisition. The atlas and structure maps were created using nonrigid groupwise registration and label-transfer techniques. Comparison and Validation: The generated atlas was compared against other atlases to study the population-specific trends. Results: The atlas-based comparison indicated a signifi cant difference between the global size of Indian and Caucasian brains. This difference was noteworthy for all three global measures, namely, length, width, and height. Such a comparison with the Chinese and Korean brain templates indicate all 3 to be comparable in length but signifi cantly different (smaller) in terms of height and width. Conclusions: The findings confirm that there is significant difference in brain morphology between Indian, Chinese, and Caucasian populations.


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Online since 20th March '04
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