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Year : 2011  |  Volume : 59  |  Issue : 4  |  Page : 558--565

Pluripotent stem cells - A review of the current status in neural regeneration

1 Department of Neurosurgery, CARE The Institute of Medical Sciences, Hyderabad, Andhra Pradesh, India
2 CLRD, Deccan College of Medical Sciences, Hyderabad, Andhra Pradesh, India

Correspondence Address:
Syed Ameer Basha Paspala
Department of Neurosurgery, CARE The Institute of Medical Sciences, Exhibition Road, Nampally, Hyderabad - 500 001, Andhra Pradesh
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/0028-3886.84338

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Pharmacological or neurosurgical therapies currently in practice to treat the damage in various neurodegenerative disorders are not efficient in preventing progression or cure of these progressive neurodegenerative processes. Recently, a new approach, cell therapy using stem cell, is being evaluated. However, the use of this therapy in the treatment of these neurological diseases is highly restricted, mainly owing to several technical difficulties and limitations. The strategy of isolation and characterization of neural stem cells from various sources will probably provide a major impetus and open up an interesting, novel therapeutic modality for several neurodegenerative disorders. The high regenerative potential of damaged neural tissues suggests that various embryonic/adult sources serve as a proxy for neural stem cells for cell-based therapy.


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Online since 20th March '04
Published by Wolters Kluwer - Medknow