| REVIEW ARTICLE |
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| Year : 2007 | Volume
: 55
| Issue : 3 | Page : 274--281 |
Craniocerebral aspergillosis in immunocompetent hosts: Surgical perspective
Muhammad Shahzad Shamim1, Arshad A Siddiqui1, Syed Ather Enam1, Ahmed Ali Shah1, Rashid Jooma2, Saleha Anwar3
1 Division of Neurosurgery, The Aga Khan University, Karachi, Pakistan
2 Department of Neurosurgery, Jinnah Postgraduate Medical Centre, Karachi, Pakistan
3 Department of Radiology, Liaquat National Postgraduate Medical Centre, Karachi, Pakistan
Correspondence Address:
Syed Ather Enam
Section of Neurosurgery, Department of Surgery, Aga Khan University Hospital, Stadium Road Karachi
Pakistan
 Source of Support: None, Conflict of Interest: None  | Check |
DOI: 10.4103/0028-3886.35689
Craniocerebral aspergillosis is a rare but dangerous variety of central nervous system infections. Surgery is being widely recognized as the cornerstone of management. Due to the rarity of the disease, difficulty and delay in diagnosis and poor outcome, there is very little in the literature regarding the various surgical strategies that may be adopted in these patients. Early aggressive surgery followed by chemotherapy offers the best chances. Surgical planning would depend upon the type and location of the disease process as well as the condition of the patient. Perioperative care holds immense importance and knowledge of possible complications is essential. Aspergillosis of the central nervous system is difficult to diagnose and equally difficult to treat. Surgery remains the cornerstone of management followed by systemic antifungal medications. Results are better in immunocompetent patients as compared to those who are immunocompromised.
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