| REVIEW ARTICLE |
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| Year : 2007 | Volume
: 55
| Issue : 3 | Page : 221--225 |
Fungal infections of the central nervous system: The clinical syndromes
J.M.K Murthy
Department of Neurology, The Institute of Neurological Sciences, CARE Hospital, Hyderabad, India
Correspondence Address:
J.M.K Murthy
Department of Neurology, CARE Hospital, Exhibition Road, Nampally, Hyderabad - 500 001
India
 Source of Support: None, Conflict of Interest: None  | Check |
DOI: 10.4103/0028-3886.35682
Fungal infections of the central nervous system (CNS) are being increasingly diagnosed both in immunocompromised and immunocompetent individuals. Sinocranial aspergillosis is more frequently described from countries with temperate climates, more often in otherwise immunocompetent individuals. The clinical syndromes with which fungal infections of the CNS can present are protean and can involve most part of the neuroaxis. Certain clinical syndromes are specific for certain fungal infections. The rhinocerebral form is the most common presenting syndrome with zygomycosis and skull-base syndromes are often the presenting clinical syndromes in patients with sinocranial aspergillosis. Subacute and chronic meningitis in patients with HIV infection is more likely to be due to cryptococcal infection. Early recognition of the clinical syndromes in an appropriate clinical setting is the first step towards achieving total cure in some of these infections.
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