| REVIEW ARTICLE |
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| Year : 2007 | Volume
: 55
| Issue : 3 | Page : 216--220 |
Immunopathogenesis of central nervous system fungal infections
John Dotis, Emmanuel Roilides
3rd Department of Pediatrics, Aristotle University, Hippokration Hospital, GR 54642 Thessaloniki, Greece
Correspondence Address:
Emmanuel Roilides
3rd Department of Pediatrics, Aristotle University, Hippokration Hospital, Konstantinoupoleos 49, GR-546 42 Thessaloniki
Greece
 Source of Support: None, Conflict of Interest: None  | Check |
DOI: 10.4103/0028-3886.35681
Fungal infections of the central nervous system (CNS) evoke humoral and cellular immune responses with the scope to enable the host to eliminate the pathogen. Immunopathogenesis of CNS fungal infections remains incompletely understood, with most of our understanding coming from studies on experimentally infected animals. However, activation of brain resident cells combined with relative expression of immunoenhancing and immunosuppressing cytokines and chemokines may play a determinant role and partially explain immunopathogenesis of CNS fungal infections.
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