Atormac
briv
Neurology India
menu-bar5 Open access journal indexed with Index Medicus
  Users online: 1003  
 Home | Login 
About Editorial board Articlesmenu-bullet NSI Publicationsmenu-bullet Search Instructions Online Submission Subscribe Videos Etcetera Contact
  Navigate Here 
 »   Next article
 »   Previous article
 »   Table of Contents

 Resource Links
 »   Similar in PUBMED
 »  Search Pubmed for
 »  Search in Google Scholar for
 »Related articles
 »   Citation Manager
 »   Access Statistics
 »   Reader Comments
 »   Email Alert *
 »   Add to My List *
 * Requires registration (Free)
 

 Article Access Statistics
    Viewed8183    
    Printed143    
    Emailed9    
    PDF Downloaded106    
    Comments [Add]    
    Cited by others 1    

Recommend this journal

 

 ORIGINAL ARTICLE
Year : 2004  |  Volume : 52  |  Issue : 1  |  Page : 79--81

Cerebral blood flow velocity changes under nitrous oxide halothane anesthesia in patients with frontotemporal gliomas: A comparison of the normal and abnormal cerebral hemispheres


1 J. N. Medical College, Belgaum, India
2 National Institute of Mental Health and Neurosciences, Bangalore - 560029, India

Correspondence Address:
G S Umamaheswara Rao
National Institute of Mental Health and Neurosciences, Bangalore - 560029
India
Login to access the Email id

Source of Support: None, Conflict of Interest: None


PMID: 15069245

Rights and PermissionsRights and Permissions

Background: Regional differences in vascular response to anesthetic agents in brain areas with and without tumors have not been investigated till now. The existence of such differences may influence the regional distribution of cerebral blood flow under anesthesia. Material and Methods: In 8 patients with frontotemporal gliomas, middle cerebral artery blood flow velocity (Vmca), pulsatality index (PI) and resistance index (RI) were determined in the normal and pathological cerebral hemispheres before and after stable nitrous oxide-halothane anesthesia. Results: During halothane anesthesia, there was an increase in Vmca both in the normal cerebral hemisphere (69 ± 11 to 100 ± 38 cm/s; P = 0.05) and the hemisphere with tumor (65 ± 17 to 83 ± 28 cm/s; P = 0.04). A significant decrease in the pulsatality index and the resistance index was also observed in both the hemispheres (P < 0.05). The percentage changes of Vmca,, PI and RI in both the hemispheres after anesthesia were not significantly different. Conclusions: In patients with cerebral tumors, nitrous oxide-halothane anesthesia causes comparable changes of cerebral blood flow velocities in the hemisphere with tumor and the normal hemisphere.






[FULL TEXT] [PDF]*


        
Print this article     Email this article

Online since 20th March '04
Published by Wolters Kluwer - Medknow