| ORIGINAL ARTICLE |
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| Year : 2003 | Volume
: 51
| Issue : 2 | Page : 203--205 |
Ventilatory management of respiratory failure in patients with severe Guillain-Barré syndrome
AN Aggarwal1, D Gupta1, V Lal2, D Behera1, SK Jindal1, S Prabhakar2
1 Departments of Pulmonary Medicine, Postgraduate Institute of Medical Education and Research, Chandigarh, India
2 Departments of Neurology, Postgraduate Institute of Medical Education and Research, Chandigarh, India
Correspondence Address:
S K Jindal
Departments of Pulmonary Medicine, Postgraduate Institute of Medical Education and Research, Chandigarh
India
 Source of Support: None, Conflict of Interest: None  | Check |
PMID: 14571003 
Guillain-Barré syndrome (GBS) is the commonest peripheral neuropathy causing ventilatory failure, and 10-30% patients may require respiratory support. Records of 11 adult patients of GBS in respiratory failure, admitted to the Respiratory Intensive Care Unit (RICU) of our institute for mechanical ventilation over a four-year period, were studied. Six patients received intravenous immunoglobulin. The median duration of mechanical ventilation was 38 days. Seven patients underwent tracheostomy. Four patients were ventilated for less than 2 weeks and 3 for more than 2 months each. Seven developed ventilator-associated pneumonia and/or sepsis. Three patients died in, and two shortly after discharge from RICU; all had systemic problems or complications of hospitalization.
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