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Year : 2001  |  Volume : 49  |  Issue : 3  |  Page : 287--90

Febrile status epilepticus as the first presentation of cortical developmental malformation : report of 2 cases.

Department of Internal Medicine, Dayanand Medical College, Ludhiana, Punjab-141 001, India., India

Correspondence Address:
G Singh
Department of Internal Medicine, Dayanand Medical College, Ludhiana, Punjab-141 001, India.
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Source of Support: None, Conflict of Interest: None

PMID: 11593248

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Cortical developmental malformations are an important cause for epilepsy. The epileptic disorder usually begins with sporadic seizures, followed by gradually increasing seizure frequency and culminating in epilepsia partialis continua. We report the de-novo occurrence of focal status epilepticus accompanying hyperpyrexia in two male children, aged 18 months and 4 years. One child had prior neuro-developmental delay, while in the other, developmental milestones were normal. In both instances, there were no seizures prior to the presenting neurological illness. Cerebrospinal fluid examination was normal in both the cases. Magnetic resonance imaging revealed extensive pachygyria in one patient and focal cortical thickening in the other. Therefore, cortical developmental malformation may be suspected as an underlying aetiology in children presenting with de-novo status epilepticus and hyperpyrexia.


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Online since 20th March '04
Published by Wolters Kluwer - Medknow