Neurology India
menu-bar5 Open access journal indexed with Index Medicus
  Users online: 778  
 Home | Login 
About Editorial board Articlesmenu-bullet NSI Publicationsmenu-bullet Search Instructions Online Submission Subscribe Videos Etcetera Contact
  Navigate Here 
 »   Next article
 »   Previous article
 »   Table of Contents

 Resource Links
 »   Similar in PUBMED
 »  Search Pubmed for
 »  Search in Google Scholar for
 »   Citation Manager
 »   Access Statistics
 »   Reader Comments
 »   Email Alert *
 »   Add to My List *
 * Requires registration (Free)

 Article Access Statistics
    PDF Downloaded0    
    Comments [Add]    

Recommend this journal


Year : 1998  |  Volume : 46  |  Issue : 2  |  Page : 82--93

Neurological complications of HIV infection.

Department of Neurology, Postgraduate Institute of Medical Education and Research, Chandigarh - 160 012, India

Correspondence Address:
CP Das
Department of Neurology, Postgraduate Institute of Medical Education and Research, Chandigarh - 160 012
Login to access the Email id

Source of Support: None, Conflict of Interest: None

PMID: 29508793

Rights and PermissionsRights and Permissions

More than half of HIV - infected persons develop symptomatic neurological disease. The nervous system is extensively involved with no part of the neuraxis being immune from the virus. Beisdes the brain and spinal cord, the peripheral nerves and muscles may be affected. Neurological complications typically occur with advanced disease and profound immunosuppression, hence a knowledge of the CD4 lymphocyte count is of paramount importance. Since many of the conditions are amenable to treatment, a proper diagnosis and therapy may decrease morbidity in the already curtailed life span of the patient. Some opportunistic neurological infection is a result of latent/persistent infection requiring lifelong secondary prophylaxis e.g. toxoplasma encephalitis and cryptococcal meningitis. Neuroaids does not follow the law of parsimony i.e. a single entity may not be responsible for the entire constellation of signs and symptoms. HIV infection is the commonest cause of dementia in people under the age 50 in thedeveloped world. Cryptococcosis is the commonest infection affecting the nervous system in HIV positive patients. Tuberculosis has seen a resurgence following the out break of AIDS. CNS lymphoma is the commonest cause of raised ICP followed by tuberculoma, toxoplasmosis and brain abscess. Most patients with paraparesis have a typical HIV associated vacuolar myelopathy. A distal predominantly sensory neuropathy is the initial feature of insult to peripheral nerves. Muscle involvement may be due to polymyositis and HIV associated wasting syndrome but may also be aggravated by drugs (e.g. zidoudine).

[PDF Not available]*

Print this article     Email this article

Online since 20th March '04
Published by Wolters Kluwer - Medknow