Neurology India
menu-bar5 Open access journal indexed with Index Medicus
  Users online: 1484  
 Home | Login 
About Editorial board Articlesmenu-bullet NSI Publicationsmenu-bullet Search Instructions Online Submission Subscribe Videos Etcetera Contact
  Navigate Here 
 »   Next article
 »   Previous article
 »   Table of Contents

 Resource Links
 »   Similar in PUBMED
 »  Search Pubmed for
 »  Search in Google Scholar for
 »   Citation Manager
 »   Access Statistics
 »   Reader Comments
 »   Email Alert *
 »   Add to My List *
 * Requires registration (Free)

 Article Access Statistics
    PDF Downloaded0    
    Comments [Add]    
    Cited by others 1    

Recommend this journal


Year : 1997  |  Volume : 45  |  Issue : 4  |  Page : 231--239

Normal pressure hydrocephalus role of radionuclide cisternography.

Department of Neurology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow - 226 014, Uttar Pradesh, India

Correspondence Address:
D Ghosh
Department of Neurology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow - 226 014, Uttar Pradesh
Login to access the Email id

Source of Support: None, Conflict of Interest: None

PMID: 29513281

Rights and PermissionsRights and Permissions

Seventeen patients with clinical and radiological features of normal pressure hydrocephalus (NPH) underwent isotope cisternography after instilling 2-3 mCi 99m-Technetium labelled Diethylene triamine pentacetic acid (DTPA) through lumbar puncture. Detailed analysis of the images taken by Gamma camera at 1,2,4 and 24 hours was done. Features of early ventricular reflux, absent or patchy radioactivity at the surface of brain and persistent ventricular reflex at 24 hours (suggesting NPH) were looked for. Depending upon patient's response to repeated CSF taps, shunt surgery was offered to the responsive group. All these patients were followed for a mean period of 11 months. Gait apraxia preceding dementia, presence of urinary incontinence and CT head picture of increased periventricular lucency predicted good response to shunt. Presence of associated diseases predicted the opposite. The sensitivity of persistent ventricular reflux at 24 hours in predicting a good response to shunt surgery was 87.5 and specificity was 77.8. Significant loss or absence of activity at surface of the brain had a sensitivity of 62.5 and specificity of 88.89. Our study indicates that radionuclide cisternography is a useful investigation for NPH in combination with clinical and radiologic studies.

[PDF Not available]*

Print this article     Email this article

Online since 20th March '04
Published by Wolters Kluwer - Medknow