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| Year : 1995 | Volume
: 43
| Issue : 1 | Page : 1--10 |
Motor recovery and therapeutic interventions.
AB Taly, BH Dobkin
Department of Neurology, National Institute of Mental Health and Neuro Sciences (NIMHANS), Bangalore - 560029
Correspondence Address:
AB Taly
Department of Neurology, National Institute of Mental Health and Neuro Sciences (NIMHANS), Bangalore - 560029
 Source of Support: None, Conflict of Interest: None  | Check |
PMID: 29542467 
Loss of motor function due to damage to nervous system is an important cause of disability among neurologically ill patient. Recent work in man and experimental animals has suggested that motor control is not only a function of cerebral cortex but also depends significantly on circuits in the spinal cord. A variety of mechanisms for natural recovery from motor paralysis have been proposed. These include dendritic sprouting, synaptogenesis, restoration of axonal transport, remyelination, unmasking of alternative pathways, removal of the effect of diaschisis, alteration in neurotransmitters and bilaterality of brain function. However in many a situations these are inadequate to provide functional independence to patients. A number of rehabilitation strategies for motor retraining have therefore been used. These are traditional exercise programs, neuromuscular re-education techniques, corrective surgical interventions, EMG biofeedback and use of pharmacological agents. More recent use of treadmill training with body weight support system and functional electrical stimulation have provided promising results. The basic underlying mechanism for the use of these strategies, their efficacy and limitations require critical evaluation. Neural transplantation may open new avenues for these patients who are incapacitated due to motor dyscontrol.
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