|Year : 1993 | Volume
| Issue : 2 | Page : 73--81
Metastatic intracranial tumours : experience and review of literature.
WH Chhang, VK Kak, VK Khosla, SN Mathuriya, BS Sharma, A Pathak, MK Tewari, BI Devi, AK Banerjee, Radotra BD
, BD Gupta, S Suri, Devi B Indira
Department of Neurosurgery, Postgraduate Institute of Medical Education and Research, Chandigarh - 160012, India
Eighty five patients with histopathologically confirmed intracranial metastatic lesions were analysed retrospectively. There were 55 males and 30 females. More than half of the patients were in fourth and fifth decades. Headache (69 percent), vomiting (50 percent) and altered sensorium (46 percent) were the common presenting features. Failing vision and epileptic seizures were present in 18 percent and 15 percent of the cases, respectively. Papilloedema was present in 68 percent of patients. Motor weakness and cranial nerve involvement was found in 42 percent and 22 percent of the patients, respectively. In 87 percent of the cases the lesions were located within the cerebral hemispheres. Only 6 percent of the patients had lesions in the cerebellum. Carcinoma of the lung was responsible for 36 percent of all intracranial metastases, followed by malignancy of the gastrointestinal tract (15 percent), genito-urinary tract (7 percent) and breast (6 percent). The primary lesion could not be located in 19 percent of the cases. 80 percent patients underwent surgery and less than half of those received postoperative irradiation and chemotherapy. The immediate postoperative mortality was 21 percent. The overall survival at five years was 6 percent.
Department of Neurosurgery, Postgraduate Institute of Medical Education and Research, Chandigarh - 160012
Source of Support: None, Conflict of Interest: None
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